LIZTOX 100 Unit
Botulinum Toxin Type A
Composition: Clostridium Botulinum Toxin Type A
Ingredients:
Clostridium Botulinum Toxin Type A …… 100 Unit
Human serum albumin (vital) …… 0.5mg
Sodium Chloride (USP) …… 0.9mg
Ingredients:
Clostridium Botulinum Toxin Type A …… 100 Unit
Human serum albumin (vital) …… 0.5mg
Sodium Chloride (USP) …… 0.9mg
Appearance: A lyophilized white powder for injection in a colorless transparent vial
Dosage Form: Freeze-dried white powder for reconstitution with sterile, 0.9% sodium chloride solution (preservative free)
Storage method: Store at 2 ~ 8ºC in a refrigerator, in a hermetic container
Injection Site: Corrugator muscle/procerus muscle(forehead wrinkles), orbicularis oculi muscles(eye wrinkles), pre-tarsal orbicularis oculi(to treat blepharospasm), masseter muscle(jaw), platysma muscle(neck), dermis(skin).
Application Areas: Treatment of blepharospasm. Improvement of glabellar lines, eye wrinkles, neck wrinkles and other facial wrinkles. Relaxation of jaw muscles to provide a slimmer jawline. Reduction of pore size to provide a smoother skin appearance.
Maintenance Period: Several months (depends on individual).
LIZTOX 100 Unit
What is Liztox 100 Unit?
Liztox 100 U is a korean botox that is made of highly-purified clostridium botulinum toxin type A. Liztox 100 U is used for the correction and preventive care of mimic wrinkles. Liztox 100 U is composed of botulinum toxin type A, 0.5mg human serum albumin and 0.9mg sodium chloride.
Characteristics of Liztox 100 Unit
Liztox 100 Unit is a Korean toxin that is used to temporarily improve moderate to severe glabellar lines related to the eyebrow wrinkle muscle (corrugator muscle) and/or the procerus muscle activity. Liztox 100 U can also be used to correct other wrinkles on the face and neckline. It can also be used in the treatment of hyperhidrosis (excessive sweating) and blepharospasm (uncontrolled blinking or eyelid movement). The age group that can receive Liztox 100 Unit treatment are adults aged 16 to 65. Since botulinum toxin is metabolized very fast by the organism, the effects become visible within 3 to 7 days after the procedure. Aesthetic effects last several months, depending on the individual’s metabolism.
Liztox 100 Unit should be dissolved in sterile, preservative-free 0.9% sodium chloride solution, after which it can be injected in the desired areas.
Liztox 100 U is a korean botox that is made of highly-purified clostridium botulinum toxin type A. Liztox 100 U is used for the correction and preventive care of mimic wrinkles. Liztox 100 U is composed of botulinum toxin type A, 0.5mg human serum albumin and 0.9mg sodium chloride.
Characteristics of Liztox 100 Unit
Liztox 100 Unit is a Korean toxin that is used to temporarily improve moderate to severe glabellar lines related to the eyebrow wrinkle muscle (corrugator muscle) and/or the procerus muscle activity. Liztox 100 U can also be used to correct other wrinkles on the face and neckline. It can also be used in the treatment of hyperhidrosis (excessive sweating) and blepharospasm (uncontrolled blinking or eyelid movement). The age group that can receive Liztox 100 Unit treatment are adults aged 16 to 65. Since botulinum toxin is metabolized very fast by the organism, the effects become visible within 3 to 7 days after the procedure. Aesthetic effects last several months, depending on the individual’s metabolism.
Liztox 100 Unit should be dissolved in sterile, preservative-free 0.9% sodium chloride solution, after which it can be injected in the desired areas.
How to Use Liztox 100 Unit
Preparation process before injection procedure using Liztox 100 Unit
Preparation process before injection procedure using Liztox 100 Unit
1. Take out Liztox 100 Unit from the refrigerator
2. Before using Liztox 100 Unit, check if there are any irregularities in the product’s appearance. This product is a white freeze-dried powder in a colorless and transparent vial
3. After filling an appropriate-sized needle with an appropriate amount of sterile, preservative-free 0.9% sodium chloride solution, slowly introduce the solution into the vial. Dilute to 100 U/2.5ml (4 U/0.1ml). Check the concentration using the following table.
4. Liztox 100 U should only be mixed with sodium chloride solution. Do not mix with other types of solutions or products. If the product bubbles up or is strongly agitated, the product’s properties change or become denatured. Therefore, make sure to slowly introduce the sodium chloride solution
5. After Liztox 100 U is dissolved in the sodium chloride solution, it should be injected into the patient within 24 hours. If the mixture is not injected into the patient immediately, store in the refrigerator at 2 ~ 8ºC. Even if the mixture is stored in the refrigerator, it should still be injected in the patient within 24 hours. Also, write on the label the date and time of when the product was dissolved.After dissolving, the product should be transparent, and should not contain any abnormal substances. If the product changes color or if foreign materials are detected, do not use this product and discard immediately.
6. Liztox 100 U does not contain any preservatives. It is not recommended to use 1 vial for more than 1 patient. After usage, the remaining product should be discarded.
7. Since each botulinum toxin product may be manufactured with a different toxin unit, the toxin unit of one product cannot be converted to the unit of another product.
5. After Liztox 100 U is dissolved in the sodium chloride solution, it should be injected into the patient within 24 hours. If the mixture is not injected into the patient immediately, store in the refrigerator at 2 ~ 8ºC. Even if the mixture is stored in the refrigerator, it should still be injected in the patient within 24 hours. Also, write on the label the date and time of when the product was dissolved.After dissolving, the product should be transparent, and should not contain any abnormal substances. If the product changes color or if foreign materials are detected, do not use this product and discard immediately.
6. Liztox 100 U does not contain any preservatives. It is not recommended to use 1 vial for more than 1 patient. After usage, the remaining product should be discarded.
7. Since each botulinum toxin product may be manufactured with a different toxin unit, the toxin unit of one product cannot be converted to the unit of another product.
How to administer Liztox 100 U
To address glabellar lines (forehead wrinkles): Using a 30 gauge needle, inject the dissolved product in the corrugator muscles and the procerus muscle (a total of 5 areas). 0.1ml of the product should be injected in each area, with a total of 20 U being injected.
When injecting into the inner corrugator supercilii muscle and the medial eyebrows, inject at least 1 cm from the edge of the eye. During injection, the needle should be aimed at the upper center, and the injection volume should be accurate. Careful attention should be paid to NOT inject Liztox 100 U into the blood vessel. To prevent Liztox 100 U from being injected into the blood vessel(exudation) below the orbital ridge, place the thumb or index finger below the orbital ridge prior to injection.
The corrugator muscle and the orbicularis oculi muscle move in the middle of the forehead to make glabellar folds on the face. The procerus muscle and the depressor supercilii muscle pull the forehead downward. These muscles create frown lines or wrinkles. Because the muscle position, muscle size, and use of muscle vary from person to person, the effective dose is determined by complete observation of the patient's ability to control the implanted surface muscles.
To address glabellar lines (forehead wrinkles): Using a 30 gauge needle, inject the dissolved product in the corrugator muscles and the procerus muscle (a total of 5 areas). 0.1ml of the product should be injected in each area, with a total of 20 U being injected.
When injecting into the inner corrugator supercilii muscle and the medial eyebrows, inject at least 1 cm from the edge of the eye. During injection, the needle should be aimed at the upper center, and the injection volume should be accurate. Careful attention should be paid to NOT inject Liztox 100 U into the blood vessel. To prevent Liztox 100 U from being injected into the blood vessel(exudation) below the orbital ridge, place the thumb or index finger below the orbital ridge prior to injection.
The corrugator muscle and the orbicularis oculi muscle move in the middle of the forehead to make glabellar folds on the face. The procerus muscle and the depressor supercilii muscle pull the forehead downward. These muscles create frown lines or wrinkles. Because the muscle position, muscle size, and use of muscle vary from person to person, the effective dose is determined by complete observation of the patient's ability to control the implanted surface muscles.
To address wrinkles around the eyes: Using a 30~33 gauge needle, administer 0.1ml(4U) each on 3 areas on one of the outer regions of the orbicularis oculi muscles (6 areas on both sides, total of 24 U).
To treat blepharospasm: Blepharospasm is defined as the uncontrollable muscle movements of the eyelid. Liztox 100 Unit should be administered using a sterile, 27-30 gauge needle, and injected into the medial and lateral pre-tarsal orbicularis oculi of the upper lid and into the lateral pre-tarsal orbicularis oculi of the lower lid. The initial recommended dose is 1.25-2.5U, at 0.05 mL to 0.1 mL volume at each site. The initial effect of Liztox 100 Unit is generally seen 3 days after being injected. Full effects are seen 1 to 2 weeks after injection. The effects last approximately 3 months. If the initial treatment is deemed insufficient (i.e. effects do not last longer than 2 months), then the dose can be increased up to two-fold in repeat treatment sessions. However, there seems to be little benefit from injecting more than 5.0 U per injection site. Patients may develop a tolerance if treatments for blepharospasm are administered more frequently than every three months. The cumulative dose of Liztox 100 Unit should not exceed 200 U in a 30-day period.
To address the masseter(jaw) muscle: Before getting the injections, it is important to have a consultation with a medical professional that will examine the jaw and face area to determine the injection site. A medical professional will clean the skin before the injection to reduce the risk of infection. A topical anesthesia to numb the area may be used. Next, the doctor will insert the thin needle into the masseter muscle. After the procedure is completed and the toxin is injected, the needle will be slowly withdrawn. The procedure may be repeated on the other side of the face.
It is important to AVOID rubbing and placing pressure on the treated area for 24 hours.
To treat neck wrinkles: During the injection into the neck area, it is important to contract and relax the platysma muscle multiple times, in order to let the doctor evaluate and select the right area that needs the injections. With the contraction of the muscle, the lines are more visible, and the doctor can grab the muscle and inject botulinum toxin into it. As botulinum toxin weakens the muscles, the motion of the platysma muscle becomes very limited, thanks to that the neck looks smoother by softening the wrinkles and lines. Moreover, as there are no involuntary contractions, the neck appears tighter as well, indirectly improving the appearance of jowls and jawline too.
To administer as skin botox: Skin botox is created by mixing 4 to 5 times more saline solution than the traditional dilution ratio for botulinum toxin procedures. This dilutes the toxin more thinly. The diluted solution should be administered into the dermal layer (skin), which is different from the traditional technique, which administers the toxin solution into the muscle. Skin botox should be injected in small amounts in several small increments in facial areas. Effects of skin botox include the tightening of pores, the reduction of fine lines, the reduced production of oil and sweat, and overall smoother appearance of skin.
Precautions when using Liztox 100 U
Liztox 100 U should be discarded as medical waste once it has passed the expiration date. If the toxin needs to be deactivated (e.g. when spilled out), use diluted hypochlorite(0.5% or 1%) before discarding it as medical waste. Also, products that have come in direct contact with Liztox 100 U should also be discarded as medical waste.
Liztox 100 U is not recommended to be injected frequently. Frequency should not exceed one treatment every 3 months.
The recommended dosage, frequency of treatment, and administration methods of Liztox 100 U should be strictly followed. Certified professionals administering Liztox 100 U should fully understand the relevant neuromuscular and/or orbital anatomy of the treatment area, and also any alterations to the anatomy that have occurred due to prior surgical procedures. DO NOT use Liztox 100 Unit without a doctor’s prescription.
Lixtox 100 Unit and its effects may unintentionally spread and affect other areas and cause adverse symptoms. Symptoms may include asthenia, generalized muscle weakness, dysphonia, dysarthria, stuttering, urinary incontinence, breathing difficulties, dysphagia (swallowing difficulties), diplopia, blurred vision, and ptosis.
The following people SHOULD NOT receive Liztox 100 Unit:
To treat blepharospasm: Blepharospasm is defined as the uncontrollable muscle movements of the eyelid. Liztox 100 Unit should be administered using a sterile, 27-30 gauge needle, and injected into the medial and lateral pre-tarsal orbicularis oculi of the upper lid and into the lateral pre-tarsal orbicularis oculi of the lower lid. The initial recommended dose is 1.25-2.5U, at 0.05 mL to 0.1 mL volume at each site. The initial effect of Liztox 100 Unit is generally seen 3 days after being injected. Full effects are seen 1 to 2 weeks after injection. The effects last approximately 3 months. If the initial treatment is deemed insufficient (i.e. effects do not last longer than 2 months), then the dose can be increased up to two-fold in repeat treatment sessions. However, there seems to be little benefit from injecting more than 5.0 U per injection site. Patients may develop a tolerance if treatments for blepharospasm are administered more frequently than every three months. The cumulative dose of Liztox 100 Unit should not exceed 200 U in a 30-day period.
To address the masseter(jaw) muscle: Before getting the injections, it is important to have a consultation with a medical professional that will examine the jaw and face area to determine the injection site. A medical professional will clean the skin before the injection to reduce the risk of infection. A topical anesthesia to numb the area may be used. Next, the doctor will insert the thin needle into the masseter muscle. After the procedure is completed and the toxin is injected, the needle will be slowly withdrawn. The procedure may be repeated on the other side of the face.
It is important to AVOID rubbing and placing pressure on the treated area for 24 hours.
To treat neck wrinkles: During the injection into the neck area, it is important to contract and relax the platysma muscle multiple times, in order to let the doctor evaluate and select the right area that needs the injections. With the contraction of the muscle, the lines are more visible, and the doctor can grab the muscle and inject botulinum toxin into it. As botulinum toxin weakens the muscles, the motion of the platysma muscle becomes very limited, thanks to that the neck looks smoother by softening the wrinkles and lines. Moreover, as there are no involuntary contractions, the neck appears tighter as well, indirectly improving the appearance of jowls and jawline too.
To administer as skin botox: Skin botox is created by mixing 4 to 5 times more saline solution than the traditional dilution ratio for botulinum toxin procedures. This dilutes the toxin more thinly. The diluted solution should be administered into the dermal layer (skin), which is different from the traditional technique, which administers the toxin solution into the muscle. Skin botox should be injected in small amounts in several small increments in facial areas. Effects of skin botox include the tightening of pores, the reduction of fine lines, the reduced production of oil and sweat, and overall smoother appearance of skin.
Precautions when using Liztox 100 U
Liztox 100 U should be discarded as medical waste once it has passed the expiration date. If the toxin needs to be deactivated (e.g. when spilled out), use diluted hypochlorite(0.5% or 1%) before discarding it as medical waste. Also, products that have come in direct contact with Liztox 100 U should also be discarded as medical waste.
Liztox 100 U is not recommended to be injected frequently. Frequency should not exceed one treatment every 3 months.
The recommended dosage, frequency of treatment, and administration methods of Liztox 100 U should be strictly followed. Certified professionals administering Liztox 100 U should fully understand the relevant neuromuscular and/or orbital anatomy of the treatment area, and also any alterations to the anatomy that have occurred due to prior surgical procedures. DO NOT use Liztox 100 Unit without a doctor’s prescription.
Lixtox 100 Unit and its effects may unintentionally spread and affect other areas and cause adverse symptoms. Symptoms may include asthenia, generalized muscle weakness, dysphonia, dysarthria, stuttering, urinary incontinence, breathing difficulties, dysphagia (swallowing difficulties), diplopia, blurred vision, and ptosis.
The following people SHOULD NOT receive Liztox 100 Unit:
- Patients who have an allergic or hypersensitive reaction to the ingredients in this product
- Patients with neuromuscular junction disorders (dysfunction at location where nerves connect with muscles), including Myasthenia gravis, Lambert-Eaton syndrome, Amyotrophic lateral sclerosis. Using this product causes relaxation of the muscle, which can exacerbate the existing disorder.
- Patients who are pregnant, planning to get pregnant, or are currently nursing mothers
- Patients below the age of 16
Whis is Liztox 100 Unit recommended?
As Liztox 100 Unit is manufactured by one of the largest pharmaceutical companies, Huons Global Co., Ltd., Liztox 100 Unit is recommended to clients who want to use a reliable korean toxin product from a well-known company. Liztox 100 Unit’s quality is truly guaranteed as it has high levels of purity at 99.8%. As such, Liztox 100 Unit is safe to use with minimal side effects.
※ Caution
We, Medi-Fella Korea, do NOT take any responsibility for medical issues and problems that occur during cosmetic procedures.
We, Medi-Fella Korea, do NOT take any responsibility for medical issues and problems that occur during cosmetic procedures.